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Synthesis of two 14C-labelled catechol-O-methyltransferase inhibitors

✍ Scribed by Carita Karlsson; Erkki Honkanen

Publisher: John Wiley and Sons
Year: 1991
Tongue: French
Weight: 162 KB
Volume: 29
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580290214

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✦ Synopsis

14C-labelled 3-(3,4dihydroxy-5-nitrophenylmethylidene)-2,4-pentanedione (4 and 14C-labelled E-N,NdiethyI-Zcyano-3-(3,4-dih droxy 5-nitropheny1)acryl-Key words: carbon-14 labelling, synthesis, COMT-inhibitor. amide (5) have been synthesized from (carbonyl-A Clvanillin.

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