Synthesis of Trifluoroalkyl- and Fluoroaryl-Substituted 4,5-Dihydro-1H-1,2,4-triazole-5-thiones
✍ Scribed by E. B. Vasil’eva; D. V. Sevenard; O. G. Khomutov; O. A. Kuznetsova
- Book ID
- 111609284
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2004
- Tongue
- English
- Weight
- 59 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1070-4280
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## Abstract magnified image Various 4‐amino‐2,3‐dihydro‐4__H__‐triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced
## Abstract The 4,5‐dihydro‐1,2,4‐triazole Schiff base derivatives were synthesized with 4‐amino‐4,5‐dihydro‐3‐(phenoxy‐ methyl)‐1__H__‐1,2,4‐triazole‐5‐thione and substituted benzaldehydes. The chemical structures of the compounds have been confirmed by ^1^H NMR, IR spectra and elemental analysis.
The acyclic C=N double bond of the title compound, C~10~H~10~N~4~S, is __trans__ configured. The molecule is almost planar. The angle between the two rings is just 10.25 (7)°. The crystal packing is stabilized by N—H...S hydrogen bonds and π–π interactions.