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Synthesis of thromboxane A2 analog, dl-(9,11)-methano-(11,12)-amino thromboxane A2

โœ Scribed by Shunji Kosuge; Masaki Hayashi; Nobuyuki Hamanaka

Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
220 KB
Volume
23
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A synthesis of nitrogen containing thromboxane A2 analog, c-(9,11)methano-(11,12)-amino thromboxane A2 (a is described. Thromboxane A2 (TXA~) 1s an extremely unstable substance possessing very important biological actlvltles (platelet aggregation and vasoconstrlctlon).

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of thromboxane A2 analog dl-(9
Synthesis of thromboxane A2 analog dl-(9,11),(11,12)-dideoxa-(9,11),(11,12)-dimethylene thromboxane A2
โœ Shuichi Ohuchida; Nobuyuki Hamanaka; Masaki Hayashi ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 215 KB

The thromboxane A2 analog, dl-(9,11),( 11,12)-dideoxa-(9,11),(11,12)dimethylene thromboxane A2 (TX A2) has been synthesized; the compound showed high agonist activities on platelet aggregation and the aorta contracting activities. In 1975, Samuelsson et al. discovered a new family of arachidonic aci