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Synthesis of the positron-emitting radiotracer [18F]-2-fluoro-2-deoxy-d-glucose from resin-bound perfluoroalkylsulfonates

โœ Scribed by Brown, Lynda J. ;Ma, Nianchun ;Bouvet, Denis R. ;Champion, Sue ;Gibson, Alex M. ;Hu, Yulai ;Jackson, Alex ;Khan, Imtiaz ;Millot, Nicolas ;Topley, Amy C. ;Wadsworth, Harry ;Wynn, Duncan ;Brown, Richard C. D.


Book ID
118265809
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
398 KB
Volume
7
Category
Article
ISSN
1477-0520

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A combined study of the labelling methods of two important glucose-derivatives i.e. [18F]2-deoxy-2-fluoro-D-glucose ([laF]2-FDG) and [lSF]3-deoxy-3-fluoro-D-glucose ([18F]3-FDG) is described. Using [ISF]fluoride as reacting agent produced in a water target via the 180(p, n)'SF and ~60(3He, p)~SF rea