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Synthesis of the first acetylene derivatives of betulonic acid

✍ Scribed by Vasilevskii, S. F.; Govdi, A. I.; Shul’ts, E. E.; Shakirov, M. M.; Alabugin, I. V.; Tolstikov, G. A.


Book ID
110160138
Publisher
Springer
Year
2009
Tongue
English
Weight
179 KB
Volume
424
Category
Article
ISSN
0012-5008

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Synthesis of some acetylenic acids
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All of the mono-ynoic acids (excluding both terminal and conjugated acetylenic acids) of chain length C10 to C14 have been prepared. None of these acids show any useful inhibition of the enzyme PG-Synthetase which is used in the synthesis of prostaglandins from arachidonic acid.