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Synthesis of some acetylenic acids

✍ Scribed by N.W. Gilman; B.C. Holland

Publisher: Elsevier Science
Year: 1974
Tongue: English
Weight: 430 KB
Volume: 13
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(74)90023-1

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✦ Synopsis

All of the mono-ynoic acids (excluding both terminal and conjugated acetylenic acids) of chain length C10 to C14 have been prepared. None of these acids show any useful inhibition of the enzyme PG-Synthetase which is used in the synthesis of prostaglandins from arachidonic acid.

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