Synthesis of substituted cinnamides: Relationship between anticonvulsant and monoamine oxidase inhibitory properties
โ Scribed by Surendra S. Parmar; Stanley J. Brumleve; P. C. Joshi; Basheer Ali
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 383 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
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Several substituted anilino-(3-methoxy-4-substituted acet0xy)benzylidenes were synthesized and characterized by their sharp melting points and elemental analyses. All substituted benzylidenes competitively inhibited the in uitro monoamine oxidase activity of rat brain homogenates and possessed antic
Several substituted pyrazolines were synthesized and characterized, and all of these pyrazolines inhibited rat brain monoamine oxidase. Evaluation of these compounds revealed appreciable anticonvulsant activity, reflected by their ability to afford protection against pentylenetetrazol-induced seizur