Synthesis of substituted benzylidinohydrazines and their monoamine oxidase inhibitory and anticonvulsant properties
โ Scribed by Surendra S. Parmar; A. K. Gupta; T. K. Gupta; Virgil I. Stenberg
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 360 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3549
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Several substituted anilino-(3-methoxy-4-substituted acet0xy)benzylidenes were synthesized and characterized by their sharp melting points and elemental analyses. All substituted benzylidenes competitively inhibited the in uitro monoamine oxidase activity of rat brain homogenates and possessed antic
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modates only about three cupric ions, which are relatively tightly bound, while the other accommodates about 16 cupric ions, which are rather weakly bound. It is possible that the first three cupric ions bind intimately by penetrating the protein while the rest of the cupric ions bind weakly to the