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Synthesis of Substituted 1-Norbornylamines with Antiviral Activity

✍ Scribed by Martínez, A. García; Vilar, E. Teso; Fraile, A. García; de la Moya Cerero, S.; Herrero, M. E. Rodríguez; Ruiz, P. Martínez; Subramanian, L. R.; Gancedo, A. García


Book ID
123613055
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
35 KB
Volume
39
Category
Article
ISSN
0022-2623

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A series of new quinoline substituted oxiranes were synthesised by the reaction of 2-N-(chloroacetyl)-1-(4'-methyl -2'-quinolinyl) hydrazide and aromatic aldehydes. These compounds were tested against encephalomyocarditis virus (EMCV) and only two compounds exhibited protection against the virus.