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Oxiranes with quinoline substitution : Stereoselective synthesis and antiviral activity

✍ Scribed by M. Kidwai; Kaushlendra Kumar; Yogesh Goel; K.C. Srivastava

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 188 KB
Volume: 6
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(96)00125-4

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✦ Synopsis

A series of new quinoline substituted oxiranes were synthesised by the reaction of 2-N-(chloroacetyl)-1-(4'-methyl -2'-quinolinyl) hydrazide and aromatic aldehydes. These compounds were tested against encephalomyocarditis virus (EMCV) and only two compounds exhibited protection against the virus.

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