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Synthesis and Antiviral Activity of Substituted Uracils

✍ Scribed by Alexander Ivanov; Vera Tunitskaya; Olga Smirnova; Robert Buckheit; Katherine Seley-Radtke; Alexander Ozerov; Mikhail Novikov

Book ID
113458034
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
82 KB
Volume
82
Category
Article
ISSN
0166-3542

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ChemInform Abstract: Synthesis and Antiv
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Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-Ξ²-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the Ξ²-anomers of these nucleosides po