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Synthesis of some [3H]- and [14C]labelled antineoplastic

✍ Scribed by J.A. Kepler; B.D. Berrang; I.D. Correa; C.J. LeFevre; G.F. Taylor


Publisher
Elsevier Science
Year
1988
Weight
65 KB
Volume
39
Category
Article
ISSN
0883-2889

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## Abstract [^3^H]SCH 211803, at a specific activity of 1.56 Ci/mmol, was prepared by direct exchange with tritiated water and platinum metal. [^2^H~4~]SCH 211803 was prepared from [^2^H]formaldehyde in a seven step synthesis in 10% yield. [^14^C]SCH 211803 was prepared from __N__‐benzyl‐4‐hydroxy[