Absfrucf N-Substltuted lmldazolylzlnc chlorides were reacted wlth 2bromopyrldlne In the presence of Pd(PPh3)4 and a two-fold excess of ZnCl2 to afford cross-coupled products In 58-93% ylelds. Deprotection provlded convenient routes to 2-or 4(5)-(2-pyrtdlnyl)lmldazoles.
โฆ LIBER โฆ
Synthesis of protected 4-oxopipecolic acid and 4-oxolysine using a palladium-catalysed coupling process
โ Scribed by Richard F.W. Jackson; Lisa J. Graham; Alan B. Rettie
- Book ID
- 104214590
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 150 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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