Synthesis of protected 3-methylaspartic acids from glutamic anhydride via nickelacycles
✍ Scribed by Ana M. Castaño; Antonio M. Echavarren
- Book ID
- 104215950
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 168 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The syntbcais of fully protected fi-methyl sqartic acids kon~ (f)_glutamic anhydride has been achieved by mems of ring contradoe of the derived nickelacycle followed by Moe of en isocyaide. Tbe intemdate five-manbaedringnickelacycleswereisulatedandcharsctcrized~~qlically.
📜 SIMILAR VOLUMES
Various optically active tS-ketobutanolides were easily prepared in good yields, with an excellent enantiomeric purity, by acylation of organomanganese reagents with the butyrolactone acid chloride 3 prepared from natural (L)-glutamic acid. The reaction takes place in THF under mild conditions (-10°
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v