Synthesis and activity of phosphono desm
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Uroš Urleb; Stanislav Gobec; Dušan Prelog
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Article
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1995
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Springer Netherlands
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English
⚖ 312 KB
Two phosphono desmuramyldipeptide analogs, 6 and 11, were synthesized and evaluated for immunomodulatory activity. Phthalimido-and adamantyl-substituted side chains as a replacement for the N-acetylmuraminic acid were coupled with appropriate dipeptides using DPPA as the coupling reagent. Introducti