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Synthesis of [phenyl-U-14C]aryl and [8-14C]carboxy labeled tracers of vorinostat

✍ Scribed by Eric D. Soli; Matthew P. Braun

Publisher: John Wiley and Sons
Year: 2006
Tongue: French
Weight: 105 KB
Volume: 49
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.1058

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✦ Synopsis

In support of a program to develop a treatment for advanced, refractory cutaneous T-cell lymphoma, two differentially [ 14 C]-labeled forms of vorinostat, a histone deacetylase inhibitor, were synthesized for use in metabolism studies.

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