## Abstract The decapeptide cetrorelix is a novel luteinizing hormone β releasing hormone (LHβRH) antagonist. For nonclinical studies concerning absorption, distribution, metabolism and excretion (ADME) in animals the [^14^C]βlebelled compound is essential. Therefore, [Uβ^14^C]Arg cetrorelix acetat
Synthesis of 14C-labelled thyrotropin releasing hormone [pyroglutamylhistidyl-14C(U)-prolineamide]
β Scribed by George Flouret; Arthur Alter; Ronald Gendrich
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- French
- Weight
- 286 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
14C-Labelled satigrel, or 4-cyano-5-(4'-methoxy tring-U-14CI phenyl)-5-(4"methoxyphenyl)-4-pentenoic acid was synthesized for drug metabolism and pharmacokinetic studies using 4,4'-diniethoxy [ring-U-W ] benzophenone as the starting material. The radiochemical yield was 10.0%. The specific radioacti
The synthesis of 14C-labelled crotamiton, which is a fungicide, an insecticide as well as a scabicide is described. Starting from 2-bromonitrobenzene and Cu14CN, 2-toluidine, labelled with 14C at the methyl group was prepared by the following sequence of reactions : N O ~-C ~H L + -~~C O O H
## Abstract [^14^C]Aminoguanidine was synthesized by the reaction of hydrazine sulphate with barium [^14^C]cyanamide in a oneβstep synthesis, and conveniently isolated by crystallization as the bicarbonate salt. The yield was 32%.