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Synthesis of 4-hydroxy[phenyl-U-14C]coumarin

✍ Scribed by Allan K. Nadian

Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
229 KB
Volume
21
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Radiolabeled 4‐hydroxycoumarin was synthesized on a microscale by condensing [U‐^14^C]phenol and malonic acid in the presence of anhydrous zinc chloride and phosphorus oxychloride. The yield was 14% on a 0.5 mmol scale at a specific activity of 107 μCi/mmol.

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