Morpholinium salts coupled to oxazolyl moieties have been synthesized via nucleophilic substitution of a series of oxazolyl chlorides with morpholine. The oxazole moieties were first synthesized and then coupled with morpholine. The corresponding hydrochloride and methyl iodide salts were obtained,
Synthesis of Oxazolyl-Substituted Morpholinium Salts.
β Scribed by John Boulos; Christina Stujenske
- Book ID
- 101996384
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Oxazolylβ5β and furanylβ2βsubstituted imidazoles have been synthesized by coupling the two ring systems __via__ the dipolar cycloaddition of tosyl methyl isocyanide to the corresponding oxazolyl and furanyl aldimines in basic media. These substituted oxazolyl and furanylimidazole bases
## Abstract magnified image Furanyl and oxazolyl Nβsubstituted imidazoline salts were prepared by reacting furanyl and oxazolyl esters with ethylenediamine and trimethyl aluminum, followed by the addition of methyl iodide or hydrogen chloride. The piperidinium salts were prepared by treating furan