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Synthesis of furanyl and oxazolyl N-substituted piperidine and imidazoline salts as potential agonists of M1 muscarinic receptors

✍ Scribed by Andreina Aguado; John Boulos; Anladys Carreras; Angelica Montoya; Judith Rodriquez

Publisher: Journal of Heterocyclic Chemistry
Year: 2007
Tongue: English
Weight: 247 KB
Volume: 44
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570440644

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✦ Synopsis

Abstract

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Furanyl and oxazolyl N‐substituted imidazoline salts were prepared by reacting furanyl and oxazolyl esters with ethylenediamine and trimethyl aluminum, followed by the addition of methyl iodide or hydrogen chloride. The piperidinium salts were prepared by treating furanyl and oxazolyl chlorides with piperidine base, followed by the addition of methyl iodide or hydrogen chloride.

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