Synthesis of Oxazolo[4,5- c ]quinoline TRPV1 Antagonists
β Scribed by Voight, Eric A.; Daanen, Jerome F.; Kort, Michael E.
- Book ID
- 126324223
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 777 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0022-3263
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## Abstract The new pyrazolo[4,3β__c__]quinolinβ3βone derivatives 3aβc and 6aβc were prepared by the following three steps: first the preparation of ethyl 4βhydroxyquinolineβ3βcarboxylate derivatives 1 and 4 by reaction of isatoic anhydrides and ethyl malonate and ethyl acetoacetate respectively, t
## Synthesis of New Pyrazolo[4, quinolin-3-ones Derivatives and Some Oxazolo[4,5-c]quinoline-2,4-diones. -With a view to obtaining new drugs, the title compounds, which can be structurally compared to analogous compounds of known immunomodulatory activity, are prepared. -(ISMAILI,