Synthesis and antiallergic activities of 1,3-oxazolo[4,5-h]quinolines
β Scribed by Musser, John H.; Jones, Howard; Sciortino, Stanley; Bailey, Kevin; Coutts, Stephen M.; Khandwala, Atul; Sonnino-Goldman, Paula; Leibowitz, Mitchell; Wolf, Peter; Neiss, Edward S.
- Book ID
- 124082817
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 678 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2623
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## Abstract The new pyrazolo[4,3β__c__]quinolinβ3βone derivatives 3aβc and 6aβc were prepared by the following three steps: first the preparation of ethyl 4βhydroxyquinolineβ3βcarboxylate derivatives 1 and 4 by reaction of isatoic anhydrides and ethyl malonate and ethyl acetoacetate respectively, t
The configurations and preferred conformations of some perhydrooxazolo[3,4-alquinolines and of the related 3,3a,4,5-tetrahydro-1H-oxazolo[3,4-u]quinolines have been assigned on the basis of their 'H NMR spectra. Comparison of the spectra of the two sets of compounds shows the effect of replacement o