ChemInform Abstract: Synthesis of New Pyrazolo[4,3-c]quinolin-3-ones Derivatives and Some Oxazolo[4,5-c]quinoline-2,4-diones.
โ Scribed by Lhassane Ismaili; Bernard Refouvelet; Jean Francois Robert
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Synthesis of New
Pyrazolo[4,
quinolin-3-ones Derivatives and Some Oxazolo[4,5-c]quinoline-2,4-diones.
-With a view to obtaining new drugs, the title compounds, which can be structurally compared to analogous compounds of known immunomodulatory activity, are prepared. -(ISMAILI,
๐ SIMILAR VOLUMES
Some pyrazolo[3,4-c~quinoline-4-ones 1-14 and pyrazolo[3.4-c]quinoline-I ,4-diones 15-17 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The moderate binding activity of 1-5,7,9-10, 13 is attributable to the lack of the optio