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Synthesis of orthogonally protected vicinal diamines with amino acid-based skeleton

✍ Scribed by Paulina Juszczyk; Leszek Łankiewicz; Aleksandra S. Kołodziejczyk


Book ID
110550422
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
429 KB
Volume
9
Category
Article
ISSN
1573-3149

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Two synthetic strategies for the generation of differentially protected, chiral tri-amino acids have been developed. The first strategy is based on the reductive amination of a serine-derived oxazolidine aldehyde with mono N-protected ethylenediamine. The second approach involves reductive alkylatio