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Synthesis of Oligoribonucleotides Containing 2′-O-Methoxymethyl Group by the Phosphotriester Method

✍ Scribed by Efimov, Vladimir A.; Aralov, Andrey V.; Chakhmakhcheva, Oksana G.

Book ID: 115478283
Publisher: Taylor and Francis Group
Year: 2011
Tongue: English
Weight: 340 KB
Volume: 30
Category: Article
ISSN: 0732-8311
DOI: 10.1080/15257770.2011.586255

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## Abstract The synthesis of oligodeoxyribonucleotides on a cross‐linked polystyrene solid support utilizing stable mono‐ and dinucleotide phosphotriester building blocks is presented. The use of __O__^6^[2‐(__p__‐nitrophenyl)ethyl]‐2′‐deoxyguanosine derivatives yields cleaner DNA fragments by supp