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N-azidomethylbenzoyl blocking group in the phosphotriester synthesis of oligoribonucleotides

✍ Scribed by V. A. Efimov; A. V. Aralov; S. A. Grachev; O. G. Chakhmakhcheva

Book ID
111457114
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
242 KB
Volume
36
Category
Article
ISSN
1068-1620

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1,1,1,3,3,3-Hexafluoro-2-propyl group as
1,1,1,3,3,3-Hexafluoro-2-propyl group as a new phosphate protecting group for oligoribonucleotide synthesis in the phosphotriester approach
✍ Shunichi Yamakage; Masayo Fujii; Hiroshi Takaku; Masaru Uemura πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 508 KB

The 1,1,1,3,3,3-Hexafluoro-2-propyl group can be used as a new class of phosphate protecting group for the protecting group of internucleotidic bonds in the oligonucleotide synthesis by the phosphotriester approach . This protecting group is removed easily by treatment with 0 .3 M N 1 ,N 1 ,N 3 ,N''