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An azidomethyl protective group in the synthesis of oligoribonucleotides by the phosphotriester method

✍ Scribed by V. A. Efimov; A. V. Aralov; S. V. Fedunin; V. N. Klykov; O. G. Chakhmakhcheva


Book ID
111456976
Publisher
SP MAIK Nauka/Interperiodica
Year
2009
Tongue
English
Weight
233 KB
Volume
35
Category
Article
ISSN
1068-1620

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1,1,1,3,3,3-Hexafluoro-2-propyl group as
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The 1,1,1,3,3,3-Hexafluoro-2-propyl group can be used as a new class of phosphate protecting group for the protecting group of internucleotidic bonds in the oligonucleotide synthesis by the phosphotriester approach . This protecting group is removed easily by treatment with 0 .3 M N 1 ,N 1 ,N 3 ,N''