Synthesis of oligonucleotides containing pyrazolo[3,4-d ]pyrimidines: The influence of 7-substituted 8-aza-7-deazaadenines on the duplex structure and stability
β Scribed by Seela, Frank; Zulauf, Matthias
- Book ID
- 125462712
- Publisher
- Royal Society of Chemistry
- Year
- 1999
- Weight
- 303 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1472-7781
- DOI
- 10.1039/a808769e
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π SIMILAR VOLUMES
Oligonucleotides containing 7-substituted 8-aza-7-deazaguanines ( 6-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones) were prepared by automated solid-phase synthesis. A series of 7-alkynylated 8aza-7-deaza-2'-deoxyguanosines (see 4a Β± d) were synthesized with the 7-iodonucleoside 3c as starting
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