Oligonucleotides containing 7-substituted 8-aza-7-deazaguanines ( 6-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones) were prepared by automated solid-phase synthesis. A series of 7-alkynylated 8aza-7-deaza-2'-deoxyguanosines (see 4a ยฑ d) were synthesized with the 7-iodonucleoside 3c as starting
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ChemInform Abstract: Synthesis of Oligonucleotides Containing Pyrazolo[3,4-d]pyrimidines: The Influence of 7-Substituted 8-Aza-7-deazaadenines on the Duplex Structure and Stability.
โ Scribed by Frank Seela; Matthias Zulauf
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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