Oligonucleotides Containing 7-Deazaadenines: The Influence of the 7-Substituent Chain Length and Charge on the Duplex Stability
β Scribed by Frank Seela; Matthias Zulauf
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- German
- Weight
- 239 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0018-019X
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π SIMILAR VOLUMES
Oligonucleotides containing 7-substituted 8-aza-7-deazaguanines ( 6-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones) were prepared by automated solid-phase synthesis. A series of 7-alkynylated 8aza-7-deaza-2'-deoxyguanosines (see 4a Β± d) were synthesized with the 7-iodonucleoside 3c as starting
Electronic-structure calculations based upon the PariserαParrαPople semiempirical Hamiltonian were applied to short-chain oligomers of the conducting Ε½ . Ε½ . polymer poly p-phenylenevinylene PPV to study the effects of appending methoxy groups along the backbone as well as pushαpull nitro and amino