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Synthesis of Oligonucleotides Containing 5-Carboxy-2‘-deoxyuridine at Defined Sites

✍ Scribed by Berthod, T.; Pétillot, Y.; Guy, A.; Cadet, J.; Molko, D.

Book ID: 125831420
Publisher: American Chemical Society
Year: 1996
Tongue: English
Weight: 183 KB
Volume: 61
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo960614f

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## Abstract A reinvestigation into the synthesis of oligonucleotides containing 5‐(β‐D‐glucopyranosyloxymethyl)‐2′‐deoxyuridine revealed that existing procedures for the preparation of these DNA fragments suffered from decomposition at the final deprotection step. The decomposition product was iden