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Synthesis of oligonucleotides containing 5-(hydroxymethyl)-2'-deoxyuridine at defined sites

✍ Scribed by Sowers, Lawrence C.; Beardsley, G. Peter


Book ID
126062796
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
242 KB
Volume
58
Category
Article
ISSN
0022-3263

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## Abstract A reinvestigation into the synthesis of oligonucleotides containing 5‐(β‐D‐glucopyranosyloxymethyl)‐2′‐deoxyuridine revealed that existing procedures for the preparation of these DNA fragments suffered from decomposition at the final deprotection step. The decomposition product was iden