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Synthesis of No-carrier-added L- and D-[1-11C]-DOPA

✍ Scribed by J.M. Bolster; W. Vaalburg; W. Van Veen; Th. Van Dijk; H.D. Van der Molen; H. Wynberg; M.G. Woldring


Book ID
107769186
Publisher
Elsevier Science
Year
1983
Weight
224 KB
Volume
34
Category
Article
ISSN
0020-708X

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The optimal conditions for the catalytic production of [11C]HCN from [11C]CO2 were investigated. [11C]CO2 was reduced to [11C]CH4 with H2 on Ni and then converted to [11C]HCN by reaction with NH3 on Pt in a radiochemical yield of more than 95% under the optimized conditions of an NH3 concentration o