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Synthesis of Natural Products and Related Compounds using Enyne Metathesis

✍ Scribed by Miwako Mori


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
363 KB
Volume
349
Category
Article
ISSN
1615-4150

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Stereoselective Synthesis of the Natural
✍ Miguel Carda; Santiago Rodríguez; Florenci González; Encarnación Castillo; Alici 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

The stereoselective synthesis of the naturally occurring lactones osmundalactone (-)-1 and muricatacin (-)-2 is described. The key steps in each synthesis are the stereoselective addition of a Grignard reagent to a suitably protected αhydroxy aldehyde and a ring-closing metathesis.