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Synthesis of Miltirone Analogues as Inhibitors of Cdc25 Phosphatases.

✍ Scribed by Weigang Huang; Jingya Li; Wei Zhang; Yueyang Zhou; Chuanming Xie; Yu Luo; Yunfei Li; Jingli Wang; Jia Li; Wei Lu

Publisher
John Wiley and Sons
Year
2006
Weight
20 KB
Volume
37
Category
Article
ISSN
0931-7597

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✍ Seung Wook Ham; Hee Joong Park; Doo Hyeon Lim πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 134 KB

It has been recently reported that some of the CDC25 genes have been implicated in the progression of cell cycle and might display oncogenic properties in mammalian cells. Therefore, the inhibition of this phosphatase may hold promise in the treatment of human cancer. In this study, we demonstrated