𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of LL-di-myo-inositol-1,1′-phosphate: A novel inositol phosphate from Pyrococcus woesei

✍ Scribed by S. H. van Leeuwen; G. A. van der Marel; J. H. van Boom; R. Hensel


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
151 KB
Volume
113
Category
Article
ISSN
0165-0513

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Synthesis of LL, DD and LD stereoisomers of di‐myo‐inositol‐1,1′‐phosphate (DIP) could be realised by phosphitylation of properly protected L‐ or Dmyo‐inositol derivatives. It was also established that naturally occurring (+)‐DIP has the LL‐configuration.


📜 SIMILAR VOLUMES


Chiral synthesis of D-myo-inositol 1-pho
✍ Takahiko Akiyama; Naoto Takechi; Shoichiro Ozaki 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 149 KB

D-M~ -inositol l-phosphate was synthesized from L-quebrachitol via stereoselective inversion of a 3-hydroxyl group and chemoselective demethylation. Recently, inositol phosphates have stimulated considerable attention from the standpoint of its biosynthesis, function, and metabolism since the disco

Synthesis of DL-myo-inositol 1-phosphate
✍ Thomas Metschies; Carsten Schultz; Bernd Jastorff 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 122 KB

A novel method for synthesis of myo-inositol l-phosphate using phosphorus oxychloride is described an transferred to synthesis of its thiophosphate analogue. ## The inhibition of myo -inositol l-phosphatase UP1 -ase) by lithium ions is used therapeutically in treating manic-depressive illnesses '