Optically pure 1D-chiro-inositol (DCI) has been synthesized from optically inactive myo-inositol practically in four steps. The crystalline nature of most intermediates and the utilization of inexpensive reagents facilitate the economical mass production of DCI, which is expected to be used in the f
A practical three-step conversion of myo-inositol into d-myo-inositol 1-phosphate
✍ Scribed by Grzegorz M. Salamon´zyk; K.Michał Pietrusiewicz
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 147 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract Synthesis of __LL, DD__ and __LD__ stereoisomers of di‐__myo__‐inositol‐1,1′‐phosphate (DIP) could be realised by phosphitylation of properly protected __L__‐ or __D__‐__myo__‐inositol derivatives. It was also established that naturally occurring (+)‐DIP has the __LL__‐configuration.
D-M~ -inositol l-phosphate was synthesized from L-quebrachitol via stereoselective inversion of a 3-hydroxyl group and chemoselective demethylation. Recently, inositol phosphates have stimulated considerable attention from the standpoint of its biosynthesis, function, and metabolism since the disco