✦ LIBER ✦

Facile and practical synthesis of optically pure 1d-chiro-inositol from myo-inositol

✍ Scribed by Yoshiaki Takahashi; Hitoshi Nakayama; Keiki Katagiri; Kumi Ichikawa; Nobuhiro Ito; Tomohisa Takita; Tomio Takeuchi; Toshiaki Miyake

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 69 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)02178-x

No coin nor oath required. For personal study only.

✦ Synopsis

Optically pure 1D-chiro-inositol (DCI) has been synthesized from optically inactive myo-inositol practically in four steps. The crystalline nature of most intermediates and the utilization of inexpensive reagents facilitate the economical mass production of DCI, which is expected to be used in the future for treatment of Type 2 diabetes and polycystic ovary syndrome (PCOS).

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