A novel method for synthesis of myo-inositol l-phosphate using phosphorus oxychloride is described an transferred to synthesis of its thiophosphate analogue. ## The inhibition of myo -inositol l-phosphatase UP1 -ase) by lithium ions is used therapeutically in treating manic-depressive illnesses '
Synthesis of thiophosphate analogues of DL-myo-inositol 1.2-Cyclic phosphate
β Scribed by Carsten Schultz; Thomas Metschies; Bernd Jastorff
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 136 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A mixture of DLβ[^2^H~6~]myoβinositolβ1β and β4βphosphate and (meso) myoβinositolβ2β and β5βphosphate is readily prepared on a 100 milligram scale from the mixed isomers of diβOβcyclohexylideneβ[^2^H~6~]myoβinositol by phosphorylation with tetrabenzylpyrophosphate. The deblocked [^2^H~6
myo-Inositol 1,4,6-u-&phosphate, in optically inactive and active forms, was prepared in order to compare its biological activity with that of myo-inositol 1,3,4,6-tetrakisphosphate which releases Ca2+ from an intracellular store.