✦ LIBER ✦

Synthesis of labeled BCX-4208, a potent inhibitor of purine nucleoside phosphorylase

✍ Scribed by Vivekanand P. Kamath; Jesus J. Juarez-Brambila; Philip E. Morris Jr

Book ID: 112073787
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 73 KB
Volume: 1
Category: Article
ISSN: 1942-7603
DOI: 10.1002/dta.24

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Development of a Practical Synthesis of

Development of a Practical Synthesis of a Purine Nucleoside Phosphorylase Inhibitor: BCX-4208

✍ Kamath, Vivekanand P.; Juarez-Brambila, Jesus J.; Morris, Christopher B.; Winslo 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 247 KB

Synthesis of deuterated-BCX-1777, a pote

Synthesis of deuterated-BCX-1777, a potent inhibitor of purine nucleoside phosphorylase

✍ Hollis S. Kezar III; Tracy L. Hutchison; Peter C. Tyler; Philip E. Morris Jr. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 112 KB

## Abstract BCX‐1777, a novel inhibitor of the enzyme purine nucleoside phosphorylase, mimics the charged ribosyl oxocarbenium ion formed during the transition state of the enzyme‐catalyzed CN bond cleavage of nucleosides. BCX‐1777 is a slow‐onset, tight‐binding inhibitor with a __K__~__i__~^\*^ o

Purine nucleoside phosphorylase inhibito

Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)—a novel potent and orally active immunosuppressive agent

✍ Shanta Bantia; Patrick J Miller; Cynthia D Parker; Sandya L Ananth; LaShun L Hor 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 133 KB

Potent orally bioavailable purine nucleo

Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies

✍ Shanta Bantia; Cynthia Parker; Ramanda Upshaw; Amanda Cunningham; Pravin Kotian; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 469 KB

A β-Fluoroamine Inhibitor of Purine Nucl

A β-Fluoroamine Inhibitor of Purine Nucleoside Phosphorylase

✍ Mason, Jennifer M.; Murkin, Andrew S.; Li, Lei; Schramm, Vern L.; Gainsford, Gra 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 301 KB

Effects of a novel purine nucleoside pho

Effects of a novel purine nucleoside phosphorylase inhibitor, BCX-34, on activation and proliferation of normal human lymphoid cells

✍ Robert M. Conry; Shanta Bantia; Heather S. Turner; Daunte L. Barlow; Karen O. Al 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 154 KB