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Synthesis of imidazo[1,2- a] pyridines directly from methyl or methylene ketones. iodination of imidazo[1,2-a] pyridines

✍ Scribed by N. O. Saldabol; S. A. Giller

Book ID
112441738
Publisher
Springer US
Year
1976
Tongue
English
Weight
682 KB
Volume
12
Category
Article
ISSN
0009-3122

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The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.