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Diastereoisomeric Imidazo[1,2-a]pyridines

✍ Scribed by Richard Kubík; Jan Němeček; Stanislav Böhm; Martin Hradilek; Josef Kuthan

Book ID
111729671
Publisher
Royal Society of Chemistry
Year
1995
Tongue
English
Weight
96 KB
Volume
5
Category
Article
ISSN
0959-9436

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Phosphorylated imidazo[1,2-a]pyridines
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The reaction of phosphorus(III) halides with imidazo [l,2-a]pyridines i n the presence of bases leads to the formation of 3-phosphorylated imidazo[l,2alpyridines. The reaction proceeds i n high yield and requires no catalysts. In the compounds obtained, in contrast to phosphorylated indolizines, th

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Solid-phase synthesis of imidazo[1,2-a]pyridines and imidazo[1,2-a]pyrimidines
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The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.