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Synthesis of Imidazo[1,2-a]pyridines as Antiviral Agents

✍ Scribed by Snoeck, Robert; Andrei, Graciela; Chavignon, Olivier; Teulade, Jean-Claude; Witvrouw, Myriam; Balzarini, Jan; Gueiffier, Alain; Mavel, Sylvie; Lhassani, Mohammed; Elhakmaoui, Ahmed


Book ID
111674118
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
69 KB
Volume
41
Category
Article
ISSN
0022-2623

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Solid-phase synthesis of imidazo[1,2-a]p
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; GΓ©rald Guillaume πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.