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Synthesis of homoallylic amines via N-acyliminium ion reactions on solid support

โœ Scribed by Wim J.N. Meester; Floris P.J.T. Rutjes; Pedro H.H. Hermkens; Henk Hiemstra

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
222 KB
Volume
40
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

The synthesis of a library of homoallylic amines is reported. The key step in the synthesis is a one-pot Nacyliminium ion coupling involving a solid phase-bound carbamate, an aldehyde and an allylsilane under Lewis acid conditions.

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