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Synthesis of (+-)-guaiol and (+-)-7-epiguaiol

โœ Scribed by Marshall, James A.; Greene, Andrew E.


Book ID
127157445
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
603 KB
Volume
37
Category
Article
ISSN
0022-3263

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The synthesis and selective degradation
โœ James A. Marshall; Andrew E. Greene; Ronald Ruden ๐Ÿ“‚ Article ๐Ÿ“… 1971 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 163 KB

In the previous report we described the stereoselective synthesis of the acetate deriva-

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Single-crystal X-ray study T = 293 K Mean '(CยฑC) = 0.005 A รŠ R factor = 0.041 wR factor = 0.134 Data-to-parameter ratio = 9.3 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

The synthesis of (+)-hedycaryol, startin
โœ Adriaan J. Minnaard; Joannes B.P.A. Wijnberg; Aede de Groot ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 795 KB

## Starting from the readily available (-)-guaiol the germacrane sesquiterpene I+)hedycayol can be synthesized in a 7 steps reaction sequence in an overall yield of 16%. Additionally, (+)-peudesmol has been synthesized, also starting from I-)-guaiol.

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โœ Hitoshi Minato ๐Ÿ“‚ Article ๐Ÿ“… 1961 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 214 KB

Osaka, Japan IN the preceding papers,' it was eetabliehed that both the C-4 and the C-10 methyl Bronps in guaiol (I) poeseas the a-configuration. Now the question remains as to whether the eubetituent at C-7 in guaiol is aor $-oriented. In thin rxperiment, an attempt was made to determine the absolu