Synthesis of (+-)-guaiol and (+-)-7-epiguaiol
โ Scribed by Marshall, James A.; Greene, Andrew E.
- Book ID
- 127157445
- Publisher
- American Chemical Society
- Year
- 1972
- Tongue
- English
- Weight
- 603 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In the previous report we described the stereoselective synthesis of the acetate deriva-
Single-crystal X-ray study T = 293 K Mean '(CยฑC) = 0.005 A ร R factor = 0.041 wR factor = 0.134 Data-to-parameter ratio = 9.3 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
## Starting from the readily available (-)-guaiol the germacrane sesquiterpene I+)hedycayol can be synthesized in a 7 steps reaction sequence in an overall yield of 16%. Additionally, (+)-peudesmol has been synthesized, also starting from I-)-guaiol.
Osaka, Japan IN the preceding papers,' it was eetabliehed that both the C-4 and the C-10 methyl Bronps in guaiol (I) poeseas the a-configuration. Now the question remains as to whether the eubetituent at C-7 in guaiol is aor $-oriented. In thin rxperiment, an attempt was made to determine the absolu