Synthesis of fragments of human β-lipotropin, βh-LPH. Part II. The synthesis of βh-LPH-(61-91), βh-endorphin
✍ Scribed by J. W. van Nispen; W. A. A. J. Bijl; H. M. Greven
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 591 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0165-0513
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✦ Synopsis
Abstract
The classical fragment condensation approach was used to synthesize the hentriacontapeptide human β‐endorphin [β~h~‐LPH‐(61‐91)].
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## Abstract The synthesis of the hexadecapeptide des‐1‐tyrosine‐γ‐endorphin, i.e. β‐LPH‐(62‐77), by means of the fragment condensation approach, is described. According to __De Wied__ and co‐workers, this peptide, or a closely related one, may function as an endogenous neuroleptic.
## Abstract The synthesis of several peptides related to β‐LPH‐(62–77) but shortened from the __N__‐terminal end, is described. In these syntheses use has been made of the classical fragment condensation approach.
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