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Synthesis of fragments of human β-lipotropin, βh-LPH. Part VI. The synthesis of des-1-tyrosine-α-endorphin and shortened peptides

✍ Scribed by W. A. A. J. Bijl; J. W. van Nispen; H. M. Greven

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
473 KB
Volume
102
Category
Article
ISSN
0165-0513

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Synthesis of fragments of human β-lipotr
Synthesis of fragments of human β-lipotropin, βh-LPH. Part IV*. The synthesis of shortened peptides related to des-1-tyrosine-γ-endorphin [β-LPH-(62-77)]
✍ H. M. Greven; J. W. van Nispen; W. A. A. J. Bijl 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 311 KB

## Abstract The synthesis of several peptides related to β‐LPH‐(62–77) but shortened from the __N__‐terminal end, is described. In these syntheses use has been made of the classical fragment condensation approach.

Synthesis of fragments of human β-lipotr
Synthesis of fragments of human β-lipotropin, βh-LPH. Part III. The synthesis of des-1-tyrosine-γ-endorphin, i.e. β-LPH-(62-77)
✍ H. M. Greven; W. A. A. J. Bijl; J. W. van Nispen 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 187 KB

## Abstract The synthesis of the hexadecapeptide des‐1‐tyrosine‐γ‐endorphin, i.e. β‐LPH‐(62‐77), by means of the fragment condensation approach, is described. According to __De Wied__ and co‐workers, this peptide, or a closely related one, may function as an endogenous neuroleptic.