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Synthesis of fragments of human β-lipotropin, βh-LPH. Part III. The synthesis of des-1-tyrosine-γ-endorphin, i.e. β-LPH-(62-77)

✍ Scribed by H. M. Greven; W. A. A. J. Bijl; J. W. van Nispen


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
187 KB
Volume
99
Category
Article
ISSN
0165-0513

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✦ Synopsis


Abstract

The synthesis of the hexadecapeptide des‐1‐tyrosine‐γ‐endorphin, i.e. β‐LPH‐(62‐77), by means of the fragment condensation approach, is described. According to De Wied and co‐workers, this peptide, or a closely related one, may function as an endogenous neuroleptic.


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Synthesis of fragments of human β-lipotr
✍ H. M. Greven; J. W. van Nispen; W. A. A. J. Bijl 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 311 KB

## Abstract The synthesis of several peptides related to β‐LPH‐(62–77) but shortened from the __N__‐terminal end, is described. In these syntheses use has been made of the classical fragment condensation approach.