The biomimetic cycZization of I-epi-gaZZicin ('8) into the e-(lB,Sa)-guaianolide ( 15) is carried out. The stereospecificity of the cycZization is explained in terms of a preferred reacting confonation ( 13). The LvZogenetic implications of this process are discussed.
The biomimetic synthesis of trans-(1β-h,5α-h)-guaianolides
✍ Scribed by Antonio G. González; Antonio Galindo; M.Mar Afonso; Horacio Mansilla; J.A. Palenzuela; M.A.Gómez Rodriguez; M. Martinez-Ripoll
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 713 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
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