A series of PET imaging studies were conducted with two fluorine-18-labeled tropane analoges, [(18)F](+)-FTT and [(18)F](+)-FCT. Both compounds possessed a high affinity and selectivity for the dopamine transporter and had a higher accumulation in the basal ganglia, a brain region having a high dens
✦ LIBER ✦
Synthesis of fluorine-18-labeled ciprofloxacin for PET studies in humans
✍ Scribed by Oliver Langer; Markus Mitterhauser; Martin Brunner; Markus Zeitlinger; Wolfgang Wadsak; Bernhard X. Mayer; Kurt Kletter; Markus Müller
- Book ID
- 117687925
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 110 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0969-8051
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## Abstract Small interfering RNAs (siRNAs), a class of macromolecules constituted by the association of two single‐stranded ribonucleic acids of short sequences, have been labelled with the positron‐emitter fluorine‐18 (__T__~1/2~: 109.8 min). The strategy involves (1) prosthetic conjugation of a